Bioequivalent Drugs: Towards A Needed Holistic Paradigm Shift?

Exercise genomics--a paradigm shift is needed: a commentary.

The overarching goal of exercise genomics is to illuminate exercise biology and behaviour in order to better understand the preventive and therapeutic values of exercise. An ancillary aim is to understand the role of genomic variation in human physical attributes and sports performance. The aim of this report is to briefly comment on the current status of exercise genetics and genomics and to s...

Towards a Paradigm Shift in Economics?

Economists and the financial community share a paradoxical fate: their economic influence is strengthened by their mistakes. We all agree that they share much of the responsibility for the crisis, yet we do not call their credibility into question. Over the past five years, the financial markets’ leading actors, notably the credit-rating agencies and major banks, have increased their ability to...

paradigm shift of health towards obesity in childhood

Playing from the inside: Holistic villages as a paradigm

In 1958, Corbu advocated a ‘new architecture’ for a ‘new man’. The omnipresence of the architect creating spaces to model a society led to architects building many sins. After that the influence of architecture in the lives of its inhabitants began to be a subject ignored. A lot of contemporary architecture limited itself to the production of design or service to capital of the day. In 1...

Old versus New Antiepileptic Drugs: Time for a Paradigm Shift?

The development of the newer antiepileptic drugs (AEDs) has increased the number of available treatment options for patients with epilepsy, making drug selection a complex task. However, studies have shown that the newer AEDs have several potential advantages over the older AEDs. Newer AEDs are less likely to cause drug-to-drug interactions, are associated with lower risk of adverse effects, an...